Affinergy develops site-specific biological systems using biofriendly linkers that selectively adhere to proteins, drugs, cells, and biomaterial surfaces in order to kickstart biology toward an intended outcome. Affinergy is focused on developing coatings and medical devices for the orthopedic and cardiovascular markets.

AFrame Digital is a technology company that is developing wireless healthcare monitoring products for the growing eldercare market, nursing homes as well as independent living markets.

ALung Technologies is a medical device company that is developing a commercial artificial lung, the Hattler Catheter. By delivering oxygen to the blood and removing carbon dioxide from the blood via a catheter, the Hattler Catheter delivers safer and less expensive respiratory support than mechanical ventilation, the current standard of care.

Andara Life Science's corporate mission is to accelerate research, development and commercialization of a platform of promising therapeutic devices and drugs for the treatment of central nervous system injury and disease.

BioFactura offers a range of process development and manufacturing services to customers and partners seeking to bring promising therapeutics, vaccines, and diagnostics to the commercial markets. In addition, BioFactura is utilizing its extensive experience to develop technologies that will add value to biopharmaceuticals as they move from discovery, to the clinic and into the marketplace.

BioVitesse develops, manufactures and markets automated in-process quality control monitoring systems and solutions for rapid bacterial detection and identification for the industrial microbiological markets.

Calypso Medical Technologies is a medical device company dedicated to improving the delivery of cancer of targeted cancer therapies. Its commitment is to solve the problems associated with organ motion during radiation treatment by developing technology that provides accurate, objective and continuous knowledge of the treatment site during radiation therapy. Calypso Medical Technologies' system operates without ionizing radiation or subjective interpretation of images.

CardioMetrix makes implantable devices for the management of congestive heart failure.

Cerionx develops technology-based state-of-the-art products for laboratory research applications in life science companies. The TipCharger System, a method to clean pipet tips released in January 2005, is covered by two issued U.S. Patents and has multiple U.S. and international patents pending.

Cyto Pulse is a medical device company that develops electric field based devices for use in vaccine delivery, vaccine production, personal vaccine production, gene therapy, and hybridoma production.

Design Medical develops heart surgery solutions that claim to reduce complications, improve outcomes and save hospitals money.

DrugRisk Solutions provides tools for individuals and institutions dealing with substance abuse by providing effective, convenient and cost-effective prevention tools. It is focused on developing rapid onsite and laboratory hair tests and complementary products to promote convenient, incentivized drug prevention.

ForHealth Technologies develops automated devices for intravenous drug preparation. ForHealth Technologies is committed to increasing patient safety and decreasing operating costs by automating the preparation of small-volume injectable medications in health care organizations worldwide. Offering safety, accuracy, efficiency and reliability, its IntelliFill i.v. automates the preparation of i.v. syringes, greatly enhancing both the safety of patients and the efficiency of hospital pharmacies.

HemCon develops, manufactures and markets innovative dressings and wound care technologies to control bleeding and infection resulting from trauma or surgery. The HemCon Bandage is designed for use by first responders in military, emergency medical and other out-of-hospital environments where the rapid control of bleeding is of critical importance.

Inovise Medical’s AUDICOR technology combines automated heart sound detection and analysis with advanced electrocardiography, and presents both graphical and textual results in a comprehensive single-page format. AUDICOR enables clinicians to rapidly and accurately assess patients presenting with symptoms of acute heart failure, acute coronary syndrome, and other high-risk cardiac conditions, resulting in earlier administration of definitive therapy.

Interventional Imaging is a medical device company focused on vascular imaging and the detection and treatment of vulnerable plaque in the coronary arteries of the heart.

Kereos develops products designed to provide more effective detection and treatment of cancer, the first two of which are expected to enter clinical trials for solid tumors in 2006. Kereos' proprietary technology pairs diagnosis and therapy by targeting imaging agents or therapeutics specifically to the disease site. In addition to advancing its internal pipeline, Kereos is working on the development and commercialization of cardiovascular disease magnetic resonance imaging (MRI) agents and Philips Medical Systems on the development of molecular imaging systems.

Kinetic Muscles is a startup medical device company. It makes a line of biofeedback training devices that allow stroke patients to perform part of their neurological rehabilitation program at home. KMI released its first product, Hand Mentor, to the market early in 2003. The Hand Mentor is sold to physical and occupational therapy clinics as well as directly to patients.

Light Sciences Corporation includes two companies developing Light Infusion Technology (Litx), to treat significant unmet medical needs in cardiovascular and eye disease. Light Sciences also continues to research novel applications for Litx in other important disease targets. Litx is a combination product comprising a proprietary photoreactive agent, LS11, activated by proprietary non-coherent light infusion devices. The target for Litx is small poorly formed blood vessels that support the development of abnormal tissues in proliferative diseases.

LipoSonix is a medical device company developing products for non-invasive body sculpting. The technology utilizes high-intensity ultrasound, focused through the skin, to break down adipose tissue without harming skin or underlying tissues and organs. Current clinical trials are proving the feasibility and safety of the technique. LipoSonix believes its product will become a powerful new body sculpting tool for the growing non-invasive aesthetic procedures market.

MAKO Surgical is a medical device company that is developing advanced technologies and procedures for the rapidly emerging orthopaedic minimally invasive total joint market.

MedStart is an orthopedic imaging informatics company working with orthopedic practices to implement digital imaging solutions that enable orthopedic physicians to acquire, move, share, archive and secure their data. MedStart is currently implementing digital solutions across the United States. In addition, MedStar provides digital imaging services to many professional sports teams.

Micronics is developing vitro diagnostic products for disease diagnosis, prognosis and treatment monitoring. The Company employs a core patent estate in microfluidics, the ability to miniaturize complex tests onto credit card sized disposable devices called lab cards. Tests are processed on a Micronics lab card in seconds to minutes.

Myocor is a medical device company that develops and commercializes therapeutic products to treat mitral valve insufficiency and heart failure. The Company's Shape Change Therapy combined with its technologies provides less invasive approaches to treating disease states stemming from geometrically remodeled hearts. The Company has completed development, pre clinical studies, and early clinical evaluation on new technologies for the treatment of mitral regurgitation and heart failure. Myocor's current focus is on the initiation and execution of a North American based clinical study evaluating the CoapsysSystem.

Myomo provides individuals with physical disabilities with simple robotic aids that are worn and physically controlled by the user. Using cutting edge MIT-based technology, it creates a non-invasive product that promises to more fully rehabilitate patients. By creating braces that amplify strength, they give patients the ability to exercise on their own and to live more independently.